As space activities continue to accelerate, regulatory bodies are facing an unprecedented range of challenges. This keynote will examine the evolving regulatory landscape and the critical issues that will shape space governance over the next two decades. These include managing the growth of mega-constellations, addressing space debris, ensuring equitable access to orbital space, and regulating emerging technologies such as on-orbit servicing and space mining. Key thought leaders and policy experts will explore how international collaboration, adaptive regulatory approaches, and forward-thinking policies can create a resilient and sustainable space ecosystem that will ensure space remains a viable domain for future generations.